Advent calendar #1 NGS – Clonality Solutions
Next-Generation Sequencing: Does your process ensure sufficient demonstration of clonality?
Although the guidelines do not require analytical demonstration of clonal derivation, we have seen a rise in the authorities’ requests for additional documentation supporting the clonality over the past years.
High throughput sequencing methods, also known as next–generation sequencing (NGS), are a fast and reliable approach to answer the cell-line production challenges when it comes to clonality evidence.
You can access here the replay of the dedicated PathoQuest 3rd annual NGS and Biosafey Workshop session around clonality led by Pr. Nicole Borth (University of Vienna) last October.