Advent calendar #1 NGS – Clonality Solutions

Next-Generation Sequencing: Does your process ensure sufficient demonstration of clonality?

Although the guidelines do not require analytical demonstration of clonal derivation, we have seen a rise in the authorities’ requests for additional documentation supporting the clonality over the past years. ​

High throughput sequencing methods, also known as nextgeneration sequencing (NGS), are a fast and reliable approach to answer the cell-line production challenges when it comes to clonality evidence. ​

You can access here the replay of the dedicated PathoQuest 3rd annual NGS and Biosafey Workshop session around clonality led by  Pr. Nicole Borth (University of Vienna) last October.